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about INT

    INTEGRATED NANO-TECHNOLOGIES (INT)

    RAPID DIAGNOSTICS FOR BIOLOGICAL DETECTION

    INT is in the process of transitioning its molecular diagnostic platform from concept to commercialization-ready. The system is based on reverse transcriptase polymerase chain reaction (“RT-PCR”), to enable diagnostics out of the laboratory and improve the accessibility of diagnostic test results. Faster accurate diagnostic test results can improve healthcare for individuals as well as play a critical role in public health. The current COVID-19 pandemic is an event where the technology being developed can improve the ability to rapidly detect infections to control disease spread and enable better treatment. The PCR test is frequently referred to by public health agencies in the United States as the gold standard test for diagnosing COVID-19.

    INT is developing a fully automated point-of-care PCR-based diagnostic system called the PalladiumTM platform, which incorporates 1) full sample preparation, 2) reverse transcriptase PCR, and 3) electronic multiplexed sensor array. The PalladiumTM system is a platform that is capable of a wide variety of molecular diagnostic tests and can process several kinds of input samples, including swabs, saliva, sputum, blood, urine, environmental samples, and food. No changes are needed to the cartridge, reader, or sensors in order to add additional tests.

    INT’s focus has been to develop a fully automated system that minimizes the need for external processing steps so that diagnostics can be run anywhere. Diagnosis of COVID-19 infections is the initial market being targeted. INT has identified multiple additional markets where molecular identification of biologicals can be utilized, but where the currently available solutions are too complicated or expensive for market uptake. These markets include bio-surveillance and security; veterinary testing; food safety; and additional medical diagnostics for infectious disease diagnosis and genetic testing. In these markets, potential users expect the sensitivity and accuracy of molecular diagnostics, while demanding ease-of-use and affordability. The PalladiumTM system was developed with ease of use and scalability for panel tests as the prime differentiators from its competitors.

    Palladiun

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